Multicenter trial of stem cell therapy for osteoarthritis (MILES).2019 American College of Rheumatology/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip, and knee. Stem cell-based therapies for osteoarthritis: Challenges and opportunities. Mesenchymal stem cell therapy for knee osteoarthritis: 5 years follow-up of three patients. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. That said, as researchers learn more about this type of treatment, it could one day become a viable option for the treatment of OA. Until additional studies can demonstrate a clear benefit from stem cell injections, people who opt for this treatment must pay for them on their own and must understand that the treatment may not work. There is not enough evidence to prove that it works or is safe.Ĭurrently, the Food & Drug Administration (FDA) considers stem cell treatment “investigational”.There is not yet a standard procedure for preparing the injection.The American College of Rheumatology and the Arthritis Foundation (ACR/AF) do not currently recommend stem cell treatment for OA of the knee, for the following reasons: However, research into stem cell treatment for OA of the knee is somewhat limited, and the results of studies are mixed. This is often referred to as “regenerative” therapy. There is evidence that stem cell treatments work by triggering damaged tissues in the body to repair themselves. There are different types of stem cells that the body can use for different purposes. Based on certain conditions and signals in the body, stem cells are directed to where they are needed.Ī stem cell is an immature, basic cell that has not yet developed to become, say, a skin cell or a muscle cell or a nerve cell. The human body is constantly manufacturing stem cells in the bone marrow.
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